Currently tracking 11 active AI roles, up 14% versus the prior 4 weeks. Primary focus: Agent · Engineering. Salary range $129k–$228k (avg $176k).
Merck currently has 27 active AI-related job listings. The majority of these roles, 41%, are focused on agents. Engineering is the most frequent function for these positions. The company is hiring for these roles in the United States, Czech Republic, and Singapore. Frequent technology tags include fine-tuning, RAG, and agent orchestration. In the last 30 days, Merck has posted 48 new AI roles, representing a 700% increase from the previous 30-day period.
Merck currently has 34 active AI-related roles in our index. The most common open titles are: Senior Business Analyst – Automation, Analytics & AI (2), Specialist, Capability Innovation & Prototype (AI Content Delivery & Partnerships) (2), AI Developer, AI Engineer, AI Research Engineer. Most positions are in Engineering and Research.
Merck's active AI hiring is concentrated in: agents (38%), application (24%), data (24%). These categories follow a seven-stage AI lifecycle: data, pre-training, post-training, serving infrastructure, agents, evaluation, and application.
Merck is hiring AI talent in: India (11 roles), United States (7 roles), Czech Republic (7 roles), Singapore (5 roles).
Job postings at Merck most frequently reference: llm observability, model serving, fine tuning, rag, evals.
In the past 30 days, Merck has posted 48 new AI-related roles. That is a +66% change versus the prior 30 days (29 → 48).
| Title | Stage | AI score |
|---|---|---|
| Senior Data Scientist, Neuroscience Biomarker Discovery Senior Data Scientist role at Merck focused on Neuroscience Biomarker Discovery. The role involves developing and deploying advanced AI/ML methodologies to analyze proteomics and other omics data for identifying biomarkers in neurodegenerative diseases. Collaboration with AI/ML scientists, data scientists, and bench biologists is key. | Data | 7 |
| Associate Principal Scientist, Biomarker Discovery, Multiomics Seeking a scientist with expertise in multi-omics and single-cell technologies for biomarker discovery in immunology drug discovery. The role involves designing and executing laboratory experiments, collaborating with computational scientists and AIML data scientists, and evaluating emerging technologies. Requires a PhD and hands-on experience with various genomic and spatial multiomics assays, as well as computational analysis of related datasets. | — |
| 5 |
| Associate Scientist, Post Doctoral Fellow- Epstein-Barr Virus & Multiple Sclerosis - Hybrid This postdoctoral research fellow position focuses on studying the link between Epstein Barr Virus (EBV) and Multiple Sclerosis (MS) using advanced analytical methods, including machine learning and omics approaches, to identify patterns in host immune response and potential biomarkers. The role involves developing statistical models, analyzing large datasets, and collaborating with a multidisciplinary team. | Data | 5 |
| Distinguished Scientist, Vaccines & Advanced Biotechnologies Process R&D Distinguished Scientist role in Vaccines & Advanced Biotechnologies Process R&D at Merck, focusing on the process development and clinical manufacturing of vaccine drug substances. The role involves crafting scientific strategy, fostering collaborations, mentoring talent, and advising on complex technical challenges, with a requirement for experience in CMC leadership and regulatory submissions. While AI/ML is mentioned as an area of understanding, it is not the core craft of the role. | — | 5 |
| Executive Director, Outcomes Research, Pediatric Vaccines This role leads a team of outcomes research professionals to develop value evidence strategies and generate real-world and economic evidence for a portfolio of products to meet the value evidence needs of clinicians, payers, policymakers, health technology assessment (HTA)/reimbursement agencies, and health systems globally. The Executive Director has scientific and budgetary oversight for all outcomes research activities, including observational studies, surveys, systematic reviews, meta-analyses, and economic modeling. Responsibilities include overseeing the development of AMCP and Global Value Dossiers, contributing to product development and marketing strategies, and collaborating cross-functionally with clinical development, medical affairs, biostatistics, market access, commercial, and country affiliates. The role also involves managing relationships with HTA agencies and reimbursement decision makers, and disseminating value evidence through scientific congresses and publications. | — | 0 |
| Oncology Regional Medical Scientific Director (Breast) - New England & Eastern NY The Oncology Regional Medical Scientific Director is a therapeutic and disease expert in breast cancer responsible for bidirectional scientific and medical information exchange with Scientific Leaders (SLs). This role involves engaging with SLs to provide balanced, factual information about non-product areas and company products, aligning with scientific exchange, research, scientific congress support, and scientific insights. The position requires a PhD, PharmD, DNP, or MD with at least 3 years of oncology experience, preferably in breast oncology, and a strong understanding of relevant ethical guidelines and regulations. | — | 0 |
| Associate Principal Scientist, Discovery Oncology Seeking an Associate Principal Scientist with a Ph.D. and 4+ years of experience in oncology drug discovery to lead research programs. Responsibilities include designing and optimizing assays, making data-driven decisions, communicating scientific strategy, and driving early-stage discovery efforts. Requires expertise in tumor biology, immune oncology, cancer genomics, and molecular/cellular biology techniques. Preferred experience with therapeutic modalities and in vivo models. | — | 0 |
| Director, Quantitative Pharmacology & Pharmacometrics - Oncology Director level role in Quantitative Pharmacology & Pharmacometrics for Oncology at Merck, focusing on drug development from post-PCC to registration. Responsibilities include leading quantitative analyses, developing PK/PD and disease progression models, and ensuring regulatory compliance. Requires a Ph.D. with significant pharmaceutical drug development experience and proficiency in modeling software. | — | 0 |
| Senior Scientist, Biology-Discovery Senior Scientist in Merck's Infectious Disease and Vaccines department focused on the discovery and development of novel antiviral treatments. Responsibilities include designing and executing experiments to study virus biology, virus-host interactions, and immunological responses using biochemical and cell-based assays. Requires a strong background in virology, immunoassay, genomic technologies, cell biology, and animal pharmacology. | — | 0 |
| Associate Vice President, Global Clinical Development, Oncology Assets The Associate Vice President (AVP) for Global Clinical Development in Oncology at Merck is responsible for the planning, directing, and overseeing of clinical research activities for new and marketed oncology drugs. This includes study design, execution, analysis, regulatory reporting, and publication. The role involves providing scientific leadership, interacting with key opinion leaders, evaluating pre-clinical work, developing clinical strategies, managing clinical trials, and analyzing findings. The AVP will also mentor direct reports and collaborate with cross-functional teams in commercialization, regulatory affairs, and statistics. Maintaining scientific knowledge, identifying investigators, and attending scientific meetings are also key aspects. The role requires an M.D. or M.D./Ph.D., with a minimum of 10 years of industry experience in drug development or biomedical research, and at least 3 years of clinical medicine experience. Demonstrated success in running multiple studies, devising strategic initiatives, and strong communication and interpersonal skills are essential. | — | 0 |
| Associate Principal Scientist, Biology-Discovery The Associate Principal Scientist role at Merck focuses on antiviral drug discovery, specifically in developing and executing cell-based antiviral assays, analyzing data, and integrating it with other functional areas. The role involves leading from the bench, collaborating with cross-functional teams, identifying new drug targets, and mentoring junior scientists. Experience with laboratory automation and integrating new technologies is also required. | — | 0 |
| Clinical Director, Clinical Research, Ophthalmology Clinical Director (Principal Scientist) responsible for planning and directing clinical research activities for new or marketed medicines in the ophthalmology therapeutic area, spanning all phases of clinical development. This includes study design, initiation, execution, monitoring, analysis, regulatory reporting, and publication. The role involves medical oversight, supporting business development, and maintaining scientific knowledge. | — | 0 |
| Associate Principal Scientist (Associate Director) -Outcomes Research This role focuses on planning and managing real-world and economic evidence activities for pharmaceutical products to meet the value evidence needs of various stakeholders. It involves designing and executing observational studies, systematic reviews, meta-analyses, and economic modeling, as well as developing dossiers for payers and HTA agencies. The role requires collaboration with cross-functional teams and external partners, and adherence to company policies and regulations like Good Pharmacoepidemiology Practice (GPP). | — | 0 |
| Associate Principal Scientist, Respiratory Discovery Merck is seeking an Associate Principal Scientist with expertise in respiratory biology and translational research to contribute to target discovery and validation for respiratory diseases. The role involves designing and executing complex studies, integrating diverse datasets, and contributing to translational strategies within cross-functional project teams. | — | 0 |
| Distinguished Scientist, Companion Diagnostics Distinguished Scientist/Executive Director to lead Companion Diagnostics (CDx) Development teams, overseeing strategy, development, and execution of CDx projects, including digital pathology. Responsibilities include leading cross-functional teams, supervising staff, partnering with internal stakeholders, identifying novel technologies, preparing regulatory documents, and serving as a subject matter expert in diagnostic development for drug development, primarily in Oncology. | — | 0 |
| Senior Scientist, Respiratory Discovery Senior Scientist role at Merck focused on respiratory biology discovery, involving target identification, translational biology, and mechanism-of-action studies for chronic lung diseases. The role requires expertise in human-relevant in vitro and ex vivo experimental systems, primary airway epithelial biology, immune-epithelial interactions, functional assays, and translational biomarkers. Responsibilities include designing and executing studies, developing experimental systems, generating mechanistic datasets, and collaborating within multidisciplinary teams. | — | 0 |
| Principal Scientist, Translational Immunology & High-Throughput Precision Biomarkers Principal Scientist role in Translational Immunology and High-Throughput Precision Biomarkers at Merck, focusing on developing and executing large-scale translational immunology studies using human biospecimens for companion diagnostic development and biomarker discovery. The role involves hands-on laboratory experiments, assay development, and integration of multi-modal data, collaborating with data scientists and biologists. | — | 0 |
| Regional Medical Scientific Director (Medical Science Liaison) - Vaccines – AL, MS, AR, LA, TN This role is for a Regional Medical Scientific Director (MSL) in the Vaccines division, focusing on engaging with Scientific Leaders (SLs) to exchange scientific and medical information related to vaccines and vaccine-preventable diseases. The role involves maintaining scientific knowledge, answering questions, supporting scientific congresses, and facilitating discussions around research strategies and investigator-sponsored research. It requires a strong medical/scientific background and adherence to ethical and regulatory guidelines. | — | 0 |
| Senior Principal Scientist, Clinical Research, Immunology Merck is seeking a Senior Principal Scientist, Clinical Research in Immunology to lead late-stage clinical development for investigational compounds. This role involves strategic planning, study design, execution, analysis, regulatory filing, and publication, with a focus on Rheumatology, Gastroenterology, Dermatology, and pulmonary disease. The position requires an M.D., D.O., or equivalent degree, significant industry experience in drug development, and a strong track record in clinical trial design and execution within Immunology. | — | 0 |
| Senior Scientist, In Vivo Cardiometabolic Diseases Seeking a Scientist/Senior Scientist with expertise in preclinical in vivo models for cardiovascular and renal disease biology. The role involves hands-on execution of complex rodent studies, advanced physiological phenotyping, and mechanistic discovery to validate targets and influence translational strategy. Requires strong experimental design, execution, and interpretation skills, with a focus on in vivo data driving scientific decisions. | — | 0 |
| Principal Scientist, Upstream Process Development This role focuses on developing drug substance manufacturing processes for biologics, including cell culture processes and transfer to manufacturing sites. It involves leading cross-functional teams, developing CMC packages, and refining technical strategy for next-generation processing. The role also emphasizes leveraging data science and digital tools for complex problem-solving and staying current with external scientific literature. | — | 0 |
| Sr. Scientist, Clinical Operations Senior Scientist role focused on leading the scientific planning and execution of clinical trials in Ophthalmology/Retina, involving medical monitoring, data interpretation, and cross-functional collaboration within a global team. Requires strong knowledge of clinical research regulatory requirements (GCP, ICH) and analytical skills. | — | 0 |
| Scientist, Clinical Operations Scientist role focused on the scientific planning and execution of clinical trials in ophthalmology/retina, supporting the Lead Clinical Scientist and study team. Responsibilities include medical monitoring, data management, stakeholder interaction, and ensuring data quality and integrity, all while adhering to clinical research regulatory requirements like GCP and ICH. | — | 0 |
| Principal Scientist (Director) -Outcomes Research Principal Scientist (Director) in Outcomes Research for Women's Cancer at Merck. Focuses on developing tumor-level evidence strategies, assessing unmet medical needs, and characterizing disease burden, treatment patterns, and healthcare costs through observational studies. Collaborates cross-functionally with clinical development, biostatistics, market access, and commercial teams, and interacts with HTA agencies. Responsibilities include leading value evidence teams, designing studies, authoring protocols and reports, managing study contracting and budgets, and communicating research findings internally and externally. Requires a Master's degree and 4+ years of experience in a relevant discipline. | — | 0 |
| Senior Scientist, Chemistry Senior Scientist, Chemistry role at Merck focused on analytical chemistry in pharmaceutical development and supply. Responsibilities include authoring procedures, performing investigations, troubleshooting lab methods, and providing technical input for regulatory submissions and audits. Requires strong technical background, problem-solving skills, and knowledge of cGMP and Data Integrity. The role involves influencing external sites and training staff on analytical techniques. | — | 0 |
| Associate Principal Scientist, Biologics Analytical Research & Development Associate Principal Scientist in Biologics Analytical Research & Development at Merck, focused on solving complex analytical problems in biology, chemistry, and lab informatics for drug development. Responsibilities include developing, qualifying, and transferring analytical methods for therapeutic proteins, leading experimental design, and interpreting data. Requires a strong background in separations science and UPLC/HPLC analysis of biologics. | — | 0 |
| Associate Principal Scientist, Biologics Process R&D Seeking an Associate Principal Scientist for Cell Line Development in Biologics Process R&D. Responsibilities include leading cell line development and cell banking activities, authoring regulatory submissions (IND, BLA, MAA), and supporting health authority responses. Requires strong experience in mammalian cell line development, ICH guidelines, and regulatory filing support. | — | 0 |
| Senior Director, Clinical Development - Antibacterials, Antifungals, CMV & Covid 19 Senior Director role focused on clinical development and research strategy for anti-infective drugs, including protocol development, medical monitoring, and analysis of study data. Requires MD or equivalent with infectious disease expertise and significant industry experience in clinical research. | — | 0 |
| Principal Scientist, Upstream Development Principal Scientist role at Merck focused on upstream development for biologics pipeline. Responsibilities include leading cell culture process development, providing technical direction for CMC development and regulatory filings, advancing platform process strategy, and initiating collaborations for new technologies. Requires a PhD with 8+ years of industry experience in a related field, with a strong track record in upstream process development, cell culture, and data science/digital tools. Preferred experience includes advanced cell culture processes, commercial development, and machine learning/predictive modeling. | — | 0 |
| Associate Principal Scientist, In Vivo Pharmacology This role focuses on developing in vivo pharmacology strategy and pharmacodynamics (PD) and efficacy models for cardiometabolic, renal, and respiratory diseases, as well as establishing quantitative PK/PD relationship and preclinical proof-of-concept. The scientist will apply knowledge of translational animal models, in vivo technology platforms, and quantitative pharmacology to advance therapeutic programs. Responsibilities include driving in vivo pharmacology strategy, leading model development & validation, collaborating with cross-functional groups, and managing external partners. | — | 0 |
| Director, Discovery Oncology, T-Cell Engagers Director of Discovery Oncology at Merck, focusing on immune-engaging biologics and advancing oncology therapeutics. Requires deep expertise in cancer biology, immunology, T cell engagers, and a proven track record of leading scientific teams and drug discovery initiatives. | — | 0 |
| Principal Scientist, Downstream Process Development Principal Scientist role focused on downstream process development for biotherapeutics at Merck. The role involves designing purification processes, developing technical strategies, and innovating manufacturing technologies. It requires collaboration with cross-functional teams, publishing research, and mentoring staff. While AI/ML is mentioned as a preferred skill, it is not the core craft of the role. | — | 0 |
| Biologics Process Research & Development Scientist Scientist in Biologics Process Research & Development (BPR&D) at Merck, focusing on developing innovative and robust manufacturing processes for biotherapeutics. This role involves experimental design, process development, and collaboration across various scientific and manufacturing functions, with a potential to integrate digital tools for process design. | — | 0 |
| Biologics Process Research & Development, Associate Scientist Associate Scientist in Biologics Process Research & Development (BPR&D) at Merck, focusing on designing, developing, and executing robust processes for biological products. The role involves contributing to innovative manufacturing technologies, conducting experiments for unit operations, and collaborating across R&D and manufacturing teams. Experience with bioprocessing, cell culture, protein purification, and data analysis is required. | — | 0 |
| Biologics Process Research & Development , Senior Scientist This role at Merck focuses on Biologics Process Research & Development (BPR&D), aiming to efficiently develop innovative and robust manufacturing processes for biotherapeutics. Responsibilities include developing disruptive technologies, applying scientific principles to solve process development challenges, designing and conducting lab/pilot-scale studies, and collaborating with cross-functional teams. The role requires a Bachelor's, Master's, or PhD in a relevant scientific or engineering field with several years of experience, and proficiency in experimental design, data analysis, and problem-solving. Experience in upstream or downstream bioprocessing is essential. While AI/ML is mentioned as a preferred skill, the core of the role is in bioprocess development, not AI/ML model building. | — | 0 |
| Scientist, Pharmaceutical Analytical Sciences Scientist role in Pharmaceutical Analytical Sciences at Merck, focusing on laboratory-based analytical characterization and statistical data analysis for drug development. Responsibilities include supporting scientific studies, developing analytical methods, troubleshooting, documenting experiments, and authoring technical reports for regulatory submissions. Requires a Bachelor's or Master's degree in a relevant field with a minimum of 0-3 years of experience. Collaboration and communication skills are essential. | — | 0 |
| Senior Principal Scientist (Senior Director), Clinical Research, ADC Senior Principal Scientist (Senior Director) in Clinical Research for Oncology Asset therapeutic area at Merck. Responsibilities include planning and directing clinical research activities for new medicines, from early to late clinical development. This involves study design, initiation, execution, monitoring, analysis, regulatory reporting, and publication. The role also includes evaluating pre-clinical and translational work, developing clinical development strategies, and providing expert scientific opinion. | — | 0 |
| Senior Director (Senior Principal Scientist), Translational Medicine, Immunology Merck is seeking a Senior Director (Senior Principal Scientist) in Translational Medicine, Immunology. This role focuses on planning and managing the early stages of drug development, translating preclinical science into compounds for clinical assessment. Responsibilities include contributing to target identification, developing biomarker strategies, and executing early clinical development and pharmacology strategies. The ideal candidate is a physician-scientist with experience in pharmaceutical R&D, clinical research, and immunology, particularly in areas like Dermatology, Rheumatology, or Gastroenterology. | — | 0 |
| Clinical Director (Principal Scientist), Clinical Research, Immunology - Rheumatology This role is for a Clinical Director (Principal Scientist) in Immunology-Rheumatology at Merck, focusing on planning and directing clinical research activities for new and marketed medicines. Responsibilities include study design, medical oversight, analysis of findings, participation in research teams, and supporting business development. The role requires maintaining scientific knowledge, identifying investigators, and attending scientific meetings. An M.D or M.D./Ph.D. is required, along with industry or senior academic experience in drug development or biomedical research, and a demonstrated record of scientific scholarship. | — | 0 |
| Clinical Director (Principal Scientist), Translational Medicine, Immunology This role is for a Clinical Director (Principal Scientist) in Translational Medicine, focusing on the early clinical development of novel therapeutics within Immunology. The position involves leadership in designing and executing clinical development strategies, developing biomarker strategies, contributing to target identification, and providing clinical pharmacology support. The role requires an MD or MD/PhD with a strong background in basic and/or clinical translational research, a proven track record in clinical medicine or research, and a demonstrated record of scientific scholarship. | — | 0 |
| Senior Principal Scientist, Clinical Research, Immunology - Ophthalmology Senior Principal Scientist role at Merck focused on late-stage clinical research in Immunology, specifically Ophthalmology. Responsibilities include strategic planning, study design, execution, analysis, and regulatory filing for investigational compounds. Requires an MD/DO/PhD and significant experience in clinical trial design and drug development within Immunology. | — | 0 |
| Senior Clinical Director (Senior Principal Scientist), Clinical Research, RCC This role is for a Senior Clinical Director (Senior Principal Scientist) in Late Stage Oncology Clinical Research at Merck. The primary responsibility is planning and directing clinical research activities for new or marketed medicines, managing the entire cycle of clinical development from study design to regulatory reporting and publication. The role requires expertise in clinical medicine, drug development, and oncology research, with a focus on evaluating pre-clinical and translational work, developing clinical strategies, and overseeing clinical trials. | — | 0 |