Mes Systems Specialist

Merck Merck · Pharma · North Brabant, Netherlands

This role focuses on the analysis, design, implementation, and optimization of Manufacturing Execution Systems (MES), specifically Körber's PASX platform, within a highly regulated pharmaceutical/biotech environment. The specialist will support manufacturing operations, ensure system stability, drive continuous improvement, and collaborate with cross-functional teams and vendors. Key responsibilities include system design, troubleshooting, documentation, testing, validation, and ensuring GxP compliance.

What you'd actually do

  1. Analyze and design information systems and processes related to MES
  2. Support manufacturing by identifying, troubleshooting, and resolving system issues
  3. Collaborate with cross-functional teams to gather requirements and deliver effective solutions
  4. Drive continuous improvement through analysis, optimization, and innovation of MES processes
  5. Design, deploy, and maintain Körber PASX MES solutions and integrations

Skills

Required

  • Extensive experience in regulated industries (pharma, biotech, food, or similar)
  • Proven hands-on experience with Körber PASX MES systems, including integrations (Level 2–4)
  • Strong understanding of manufacturing systems, data flows, and system integrations
  • Knowledge of GxP environments, validation processes, and compliance requirements
  • Strong analytical and problem-solving skills in complex manufacturing environments
  • Experience in stakeholder management and cross-functional collaboration
  • Fluent in English

Nice to have

  • Bachelor’s, Master’s, or PhD degree in Life Sciences, Biotechnology, Pharmacology, Information Systems, or a related field
  • Experience with industrial data platforms and protocols (e.g., OPC UA, Aveva PI, Kepware)
  • Strong knowledge of databases and query languages (e.g., Oracle, PostgreSQL)
  • Understanding of OT/IT architectures (ISA-95 / ISA-99) and secure network design
  • Familiarity with system infrastructure concepts (e.g., load balancing, failover clusters)
  • Experience with Agile methodologies
  • Knowledge of Kubernetes, CI/CD pipelines, and containerized applications
  • Experience with cloud platforms (AWS, Azure)
  • Scripting skills (PowerShell or Python)

What the JD emphasized

  • Körber PASX MES systems
  • regulated industries (pharma, biotech, food, or similar)
  • GxP environments
  • validation processes
  • compliance requirements