Scientist, Dissolution & Biopharmaceutical Modeling

Eli Lilly Eli Lilly · Pharma · Indianapolis, IN

Scientist role focused on developing analytical methods and conducting experiments for early clinical formulation development of synthetic drug molecules, collaborating with formulation scientists and biopharmaceutical modeling scientists to guide drug product development from research through commercialization. Emphasizes safety, quality, regulatory, GLP/GMP, and authoring regulatory documents.

What you'd actually do

  1. Developing analytical methods and conducting experiments to aid early clinical formulation development to enable drug delivery of a broad range of synthetic drug molecules.
  2. Collaborating with formulation scientists to design experiments and guide selection and characterization of formulations for pre-clinical and early clinical drug candidates.
  3. Partnering with biopharmaceutical modeling scientists, analytical chemists, pharmaceutical scientists, and engineers to identify the appropriate drug form, formulation, and process characteristics that provide the desired drug product performance.
  4. Identifying and mitigating technical risks for the performance and production of clinical and commercial drug products.
  5. Executing with attention to safety, quality, regulatory, GLP/GMP, and legal requirements for all activities.

Skills

Required

  • B.S. in Chemistry, Biochemistry, Pharmaceutical Science, or other directly related discipline (e.g., Material Science)
  • Understanding of analytical techniques and methods for characterizing physicochemical properties of drug molecules and performance of drug products (e.g., HPLC, UV, NIR, dissolution)
  • Strong leadership, supervisor, teamwork, communication and writing skills.

Nice to have

  • Industry, research or internship experience relevant to the position is strongly preferred.
  • Knowledge of biopharmaceutics and pharmacokinetic principles, formulation development and pharmaceutical material sciences, and drug product factors impacting in vivo performance and manufacture.
  • Basic understanding of regulatory aspects pertaining to development and clinical testing of drug products.
  • General understanding of techniques and instrumentation used in characterization of pharmaceutical drug products, especially dissolution and other product performance tests.

What the JD emphasized

  • Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization and visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.