Senior Scientist (m/f/d), Preclinical Development in Animal Health With Focus on Immunology

Merck Merck · Pharma · Rheinland-Pfalz, Germany

Senior Scientist role in Preclinical Development focusing on Immunology for Animal Health at Merck. Responsibilities include scientific support for R&D, compiling and assessing profiles of compounds, planning and evaluating studies (toxicology, safety, pharmacokinetics, immunogenicity), designing and overseeing immunology and monoclonal antibody studies, and compiling reports for regulatory submissions. Requires a Veterinary Medicine degree with a PhD, experience in R&D (preferably veterinary pharma), managing animal studies (GLP), and profound knowledge in pharmacology, toxicology, and immunology. Hands-on experience with immunological assays is essential. Fluency in English and German is required.

What you'd actually do

  1. Scientifically support Research and Development for new and existing products in animal health
  2. Compile and assess pharmacological, toxicological, and immunological profiles of compounds through literature search and experimental testing
  3. Plan, conduct, and evaluate in-house and outsourced studies according to GLP guidelines, including toxicology, target animal safety, pharmacokinetics, metabolism, residue depletion, immunogenicity, and monoclonal antibody characterization
  4. Design and oversee immunology, and monoclonal antibody studies, including antigen characterization, immune response assays, and antibody efficacy testing
  5. Compile expert reports, regulatory submissions, and scientific presentations in English for authorities and internal stakeholders

Skills

Required

  • ADME
  • Biochemical Assays
  • Cell-Based Assays
  • Detail-Oriented
  • Drug Metabolism
  • English Language
  • Flow Cytometry
  • German Language
  • High Resolution Mass Spectrometry (HRMS)
  • Ligand Binding Assay
  • Liquid Chromatography-Mass Spectrometry (LC-MS)
  • Mass Spectrometry Analysis
  • Metabolite Identification
  • Pharmacodynamics
  • Pharmacokinetics
  • Pharmacotherapeutics
  • Teamwork
  • Veterinary Medicine
  • Veterinary Research

Nice to have

  • Twitter

What the JD emphasized

  • GLP guidelines