Associate Director Rwe, Pharmar&d

Tempus AI · Vertical AI · Boston, MA +1

Associate Director RWE, PharmaR&D at Tempus AI, focusing on designing and executing research projects for biopharmaceutical partners using real-world evidence and AI. The role involves computational analysis, guiding algorithm development, and incorporating LLMs and agentic workflows into research processes to advance cancer precision medicine.

What you'd actually do

  1. Lead the derivation of complex real-world endpoints using extensive coding, demonstrating deep comprehension of Tempus clinical and molecular data structures and complexity, while also serving as an expert on the methodological nuances and limitations of real-world data.
  2. Incorporate LLMs, agentic workflows, foundation models and other AI tools into day-to-day workflows to accelerate code development, discovery, documentation, review, and insight generation.
  3. Partner with big pharma clients. Become proficient in the clients’ strategies, drug modalities and pipeline to identify where the Tempus platform can add value.
  4. Work with Research, Engineering & Data Science teams across Tempus’ expansive data science community to develop and deliver innovative computational solutions.
  5. Present highly technical results and methods clearly and meaningfully to diverse sets of external stakeholders

Skills

Required

  • Expert-level proficiency in observational real-world healthcare data
  • designing and implementing complex time-to-event methodologies (survival analysis)
  • Track record of leading RWD analytical studies from initial scoping through to publication or dissemination.
  • Proficient in R, Python, and SQL
  • Strong understanding of cancer biology
  • Strong peer-reviewed publication record.
  • Adherence to good software engineering practices (version control, documentation).

Nice to have

  • Proficiency applying machine learning, statistical modeling, LLM-based coding assistants (e.g., Copilot, Cursor) and agentic frameworks to support data analysis.
  • Experience in clinical trial design (particularly Phase II-III) in the clinical development space.
  • Extensive proficiency with claims, EHR, or registry data.
  • High-level familiarity with NCCN guidelines and the ability to interpret real-world outcomes within the context of the current oncology standard of care.
  • Significant experience analyzing biomarker, genomic, or other high-dimensional molecular data alongside clinical datasets.
  • Experience with: Package development, tidyverse, Git, matplotlib, Pandas, Jupyter Notebook

What the JD emphasized

  • Expert-level proficiency in observational real-world healthcare data
  • Track record of leading RWD analytical studies from initial scoping through to publication or dissemination.
  • Strong peer-reviewed publication record.

Other signals

  • AI & LLM Innovation
  • foundation models
  • agentic workflows
  • computational analyses
  • algorithm development