JOB SUMMARY
We are seeking a highly motivated and experienced Senior Associate Scientist to join the Biology group and advance our core mission of accelerating small molecule drug discovery programs at Iambic Therapeutics. The successful candidate will have a proven track record of supporting in vitro cell-based assays to advance pre-clinical projects. The candidate will work closely with a cross-functional team that integrates machine learning, medicinal chemistry, analytical technology and biology to revolutionize small-molecule therapeutics design and discovery. This role is based at our San Diego headquarters.
KEY RESPONSIBILITIES
- Design, develop, and optimize biochemical and cell-based assays to support multiple drug discovery programs, working closely with project teams and cross-functional partners.
- Independently execute biochemical and/or cell-based assays on a weekly basis to screen and evaluate small-molecule compounds
- Partner with Chemistry and Compound Management teams to enable efficient compound screening across pipeline projects.
- Analyze and interpret experimental data and ensure scientific rigor and data quality
- Partner with cross-functional teams to QC and upload experimental data in a timely manner
- Present experimental results and project updates at team meetings
- Maintain and manage cell lines to support ongoing research projects
- Contribute to the maintenance of the biology laboratory
QUALIFICATIONS
- Associate Scientist II- Bachelor’s degree in biochemistry, pharmacology, cell biology, or other related scientific areas with a minimum of 2- years of industry experience
- Senior Associate Scientist- Bachelor’s degree in biochemistry, pharmacology, cell biology, or other related scientific areas with a minimum of 5 years of industry experience
- Hands-on experience in cell biology and routine biological assays, including techniques such as cell culture, cell proliferation assays, cytotoxicity assays, ELISA, and Western blot,
- Experience with proximity-based assays is highly desirable (e.g., HTRF, NanoBRET, AlphaLISA)
- Familiarity with HTS screening methodology is highly desirable
- Demonstrated scientific rigor with proven ability to critically evaluate data, and think independently and creatively in developing and testing new scientific hypotheses
- Excellent oral and written communication skills is required
- Highly motivated to work in a cross-functional team setting
- Flexibility and ability to quickly learn new skills and knowledge on the job
ABOUT IAMBIC THERAPEUTICS
Iambic is a clinical-stage life-science and technology company developing novel medicines using its AI-driven discovery and development platform. Based in San Diego and founded in 2020, Iambic has assembled a world-class team that unites pioneering AI experts and experienced drug hunters. The Iambic platform has demonstrated delivery of new drug candidates to human clinical trials with unprecedented speed and across multiple target classes and mechanisms of action. Iambic is advancing a pipeline of potential best-in-class and first-in-class clinical assets, both internally and in partnership, to address urgent unmet patient need. Learn more about the Iambic team, platform, pipeline, and partnerships at iambic.ai.
MISSION & CORE VALUES
Our mission is to deliver better medicines through innovations in AI-based discovery technologies. The culture and work at Iambic Therapeutics are profoundly strengthened by the diversity of our people and our differences in background, culture, national origin, religion, sexual orientation, and life experiences. We are committed to building an inclusive environment where a diverse group of talented humans work together to discover therapeutics and create technologies.
PAY AND BENEFITS
We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team. We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.