Contractor, Senior Research Associate, Cell Culture Operations

Lila Sciences Lila Sciences · AI Frontier · Alewife, Cambridge, MA · Autonomous Science Platform

Contractor, Senior Research Associate, Cell Culture Operations at Lila Sciences. Responsible for day-to-day execution and maintenance of mammalian cell culture activities, managing cell banks, performing flow cytometry, authoring SOPs, and supporting automation of cell culture workflows. Requires B.S. or M.S. with 2-3+ years of experience in cell culture and flow cytometry.

What you'd actually do

  1. Perform routine and advanced mammalian cell culture (maintenance, expansion, passaging, cryopreservation, thawing) across a range of cell lines and cell types; monitor cell health and proactively resolve culture issues.
  2. Manage and maintain cell banks (inventory, quality checks, documentation) and oversee reagent/consumable procurement to ensure uninterrupted cell supply.
  3. Perform flow cytometry / FACS acquisition and data analysis to support cell characterization, quality checks, and downstream research needs.
  4. Author, maintain, and improve SOPs for cell culture workflows; identify opportunities to streamline operations and improve consistency.
  5. Support adoption of automated or semi-automated cell culture workflows, including protocol translation, run execution/troubleshooting, and performance verification.

Skills

Required

  • B.S. or M.S. in Cell Biology, Molecular Biology, Bioengineering, or related discipline.
  • 3+ years (B.S.) or 2+ years (M.S.) of relevant experience with a strong focus on mammalian cell culture.
  • Demonstrated expertise in aseptic technique, routine and advanced cell culture, cell banking, and culture troubleshooting.
  • Hands-on experience with cell culture liquid handling techniques.
  • Experience with flow cytometry / FACS acquisition and data analysis.

Nice to have

  • Experience culturing primary human or animal cells (e.g., PBMCs, T cells, tissue-derived primary cells).
  • Experience with iPSC culture and maintenance (e.g., feeder-free systems, passaging techniques, pluripotency monitoring).
  • Experience with cell engineering approaches such as lentiviral vector (LVV) transduction or CRISPR-based editing.
  • Familiarity with inventory/LIMS platforms.