Director, R&d Neuroscience Data Science & Digital Health – Ophthalmology

Johnson & Johnson Johnson & Johnson · Pharma · Cambridge, MA +5

Director role focused on leveraging AI/ML, computer vision, and digital health technologies to accelerate drug discovery and development in ophthalmology. This involves analyzing multimodal data, developing digital endpoints, integrating real-world evidence, and applying generative AI for insights. The role emphasizes collaboration with cross-functional teams and external partners to enhance clinical trial execution and patient care.

What you'd actually do

  1. Drive the development and application of advanced AI/ML methods, including cutting-edge computer vision techniques applied to ophthalmic imaging data (e.g., Optical Coherence Tomography and fundus images), to uncover disease mechanisms and identify novel biomarkers.
  2. Lead the development and validation of novel digital endpoints. Engage with regulatory stakeholders to ensure these innovations enhance clinical trial design, improve patient monitoring and care pathways, and meet regulatory requirements.
  3. Develop and apply sophisticated statistical models using real-world and clinical data to generate insights into disease progression, treatment outcomes, and patient stratification. Leverage longitudinal disease modeling, Bayesian methodologies, and causal inference techniques to inform decision-making.
  4. Apply emerging generative AI approaches to boost data analysis and knowledge discovery, integrating diverse multimodal datasets (imaging, clinical, wearable, etc.) for a more holistic understanding of ophthalmic diseases.
  5. Partner with Clinical Development and Medical Affairs to integrate RWE into evidence generation strategies. Support trial optimization and regulatory submissions by incorporating insights from large-scale clinical datasets, electronic health records (EHRs), and other real-world data sources.

Skills

Required

  • PhD, MD, or equivalent in computational ophthalmology, neuroscience or a quantitative field
  • 8+ years of relevant industry or academic experience
  • Strong record of success in applying data science within biology/medicine
  • Experience in clinical development
  • Deep experience in computer vision and deep learning applied to biomedical imaging (especially ophthalmic imaging such as fundus photography and OCT)
  • Familiarity with model validation, reproducibility, and regulatory considerations for AI tools in healthcare

Nice to have

  • experience in ophthalmology preferred
  • Experience working with large-scale datasets

What the JD emphasized

  • AI/ML methods
  • computer vision
  • digital health
  • ophthalmology
  • clinical development
  • regulatory requirements
  • multimodal datasets
  • real-world evidence

Other signals

  • AI/ML methods
  • computer vision
  • digital health
  • drug discovery
  • clinical trial execution
  • patient stratification
  • digital biomarkers
  • generative AI
  • multimodal integration
  • real-world evidence