Role Summary
Will report to the VP, Dermatology/Respiratory Medical Lead
The Global Senior Medical Director will be the strategic external scientific face and internal point person of our Respiratory pipeline portfolio globally, advocating Pfizer I&I as a preferred development partner, supporting the operational execution of key studies, and synthesizing insights into actionable intelligence that will shape our clinical development plans to maximize the potential of early pipeline molecules in the respiratory field. Supports building the foundation of future launches to differentiate our portfolio, accelerate initiation of tailored life cycle management data generation plans, and meet the projected unmet needs of a diverse patient population.
The Global Senior Medical Director – Respiratory Pipeline Medical Lead will need to show high level of scientific and technical expertise in pulmonology+/- allergy and will benefit from an established and strong network of international KOLs in order to function as a peer and leader for medical affairs in developing this ambition.
A key element of the work will be to define the medical strategy for the Respiratory Pipeline in close collaboration with clinical development, CSI, International and US stakeholders and various cross functional partners. Collaboration across functions, creativity, solution-orientation and leadership skills are key criteria for a successful candidate while showing strong ability to prioritize and focus strategies based on specific asset requirements.
These strategies will support Pfizer´s vision to be a highly trusted partner that is providing breakthroughs to its customers.
The successful candidate will be the core Global Medicine Team member of multiple priority pipeline molecules and an integral member of the Global Medical Respiratory community as well as a Respiratory DAWG member. At the same time, he/she will partner effectively with International and US cross functional stakeholders, commercial, PHI, GPD, corporate affairs for strong alignment and an integrated approach for the Pipeline Strategy
They will be responsible for shaping and executing the medical strategy for the Respiratory pipeline portfolio. This role will ensure scientific leadership, evidence generation, and stakeholder engagement to support successful development and launch of innovative therapies in Respiratory.
Role scope and Responsibilities
This is a senior global medical leadership role with strategic accountability for the Respiratory pipeline. Global Respiratory Pipeline Medical Lead serves as the primary medical authority for early respiratory assets, representing medical in global governance and portfolio discussions and influencing cross‑functional decision‑making through scientific leadership and expertise. The role requires strong leadership through influence across functions and geographies to shape respiratory pipeline strategy and future capabilities.
Strategic leadership
- Develops and implement the global medical affairs strategy for Respiratory pipeline assets, aligned with overall business objectives.
- Provides scientific and clinical expertise to inform development plans and lifecycle management in collaboration with cross functional colleagues to develop perspectives on future treatment landscapes, unmet needs, epidemiology of disease conditions and biomarkers for prioritized programs
- Partners with early commercial development to deliver the target product profile (TPP) and medical differentiation index assessment
- Works closely with Business development on due diligence for potential external opportunities
- Supports the phase II and III respiratory clinical trials education and awareness
Accountable for uplifting respiratory scientific capability across Medical Affairs. In close collaboration with the US and International leads, including
- Internal education
- Thought partnership with non‑respiratory colleagues
- Helping establish Respiratory as a credible pillar alongside Derm
Evidence Generation & Data Strategy:
- Defines and oversees the integrated evidence plan including clinical trials, real-world evidence, and investigator-initiated studies for Respiratory/allergy pipeline.
- Leads collaborative research partnerships and strategy for independent Pfizer sponsored research
- Ensures robust data dissemination through publications, congress presentations, and scientific exchange in collaboration with the R&D team and the publication lead
Stakeholder Engagement:
- Builds and maintains relationships with key external experts, professional societies, and patient advocacy groups.
- Leads and implements globally insight generation activities, understanding the external customer perspectives through peer-to-peer interactions, data/facts/observations from field medical and advisory board meetings.
- Leads and develops data interpretation and alignment activities with internal and external partners to inform decision making and to support development of educational activities, medical strategies and tactics.
- Attends Respiratory & allergy medical congresses, interacts with key investigators and reviews literature, focusing on emerging data in MOAs relevant to our early development portfolio and provides insights to inform on the development strategy
- Responsible for future creation of the respiratory team in accordance to the respiratory portfolio evolution as well as for making strategic resourcing decisions.
Cross-Functional Collaboration:
- Partner with Clinical Development, Regulatory, and Commercial teams to ensure alignment on scientific messaging and launch readiness.
- Support development and execution of internal medical training curriculum around asset data and relevant disease area content in collaboration with the Medical Content and Communication team
- Partners with the dermatology pipeline lead to ensure a unified and aligned scientific narrative for assets that have multiple indications across Dermatology and Respiratory conditions (e.g. AD and Asthma)
- Works closely with the International and the US leads to ensure alignment of the respiratory strategy with the insights collected as well as with the regional and countries needs
Compliance & Governance:
- Maintain high ethical standards in all scientific communications.
** Qualifications**
MD
Board certification/Specialization in Pulmonology or Allergy strongly preferred
Subject matter expertise in Asthma, COPD, and emerging pulmonology indications
Comfort operating in mechanism‑driven, cross‑indication strategies, especially early phase
Minimum 5+ years of experience in Medical Affairs or Clinical Development, preferably in Respiratory or immunology
Above country experience (global or international) required
Proven track record in pipeline strategy, evidence generation, and external engagement.
Strong understanding of global regulatory and compliance frameworks.
Ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Proven track record on critical clinical decision making, commercial and regulatory implications of clinical study design elements, analysis of complex scientific data required.
Proven track record of ability to work and partner successfully with cross-functional colleagues in a matrix team setting across countries and internationally with diverse colleagues and cultures
Excellent communication, leadership, and matrix management skills.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including:
Track record of evidence generation required.
Demonstrated executional capabilities and leadership without authority in prior medical affairs roles
Strategic thinking and scientific acumen.
Ability to influence and lead in a complex, global environment.
Strong collaboration and stakeholder management skills.
Passion for innovation and improving patient outcomes
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Work Location Assignment: Hybrid - must be onsite and average of 2.5 days per week
#LI-PFE
The annual base salary for this position ranges from $274,500.00 to $457,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Medical