Post Doc – Solid-state Nmr & Peptide–formulation (mechanistic Insights)

Johnson & Johnson Johnson & Johnson · Pharma · Beerse, Antwerp, Belgium

Postdoctoral scientist role focused on understanding molecular interactions for oral peptide delivery using solid-state NMR, complementary spectroscopy, and computational modeling. The role aims to generate mechanistic insights to guide the design of new functional excipients.

What you'd actually do

  1. Develop and run ssNMR experiments (data acquisition, processing, and interpretation) to characterize molecular interactions between peptides, biomimetic membranes, and functional excipients.
  2. Apply computational modeling and data analytics to strengthen interpretation of experimental results.
  3. Generate high-quality datasets through hands-on laboratory work and in silico approaches to test mechanistic hypotheses.
  4. Translate mechanistic insights into formulation strategies to improve oral delivery of peptide candidates in discovery and development.
  5. Work safely and in compliance with applicable environmental, health, regulatory, GMP, and safety requirements.

Skills

Required

  • Ph.D. (0–3 years post-graduation) in physical chemistry, biochemistry, biophysics, or a related discipline
  • Solid understanding of solid-state NMR (ssNMR) principles, with hands-on experience operating ssNMR instrumentation and data analytics and interpretation
  • Strong understanding of solution NMR spectroscopy
  • Demonstrated digital aptitude, including effective use of data analysis, modeling, and/or computational tools to support scientific problem-solving and evidence-based decisions
  • Ability to design and conduct laboratory experiments independently
  • Ability to define and drive scientific research independently, including development of research proposals
  • Track record of scientific contributions (e.g., peer-reviewed publications, patents, and/or scientific presentations)
  • Excellent written and verbal communication skills, with the ability to clearly articulate scientific rationale and recommendations

Nice to have

  • Experience with Bruker solid-state NMR systems
  • Experience with spectroscopic techniques (e.g., CD, FTIR, UV–vis, fluorescence)
  • Familiarity with physicochemical characterization of active pharmaceutical ingredients (APIs)

What the JD emphasized

  • Solid understanding of solid-state NMR (ssNMR) principles, with hands-on experience operating ssNMR instrumentation and data analytics and interpretation
  • Track record of scientific contributions (e.g., peer-reviewed publications, patents, and/or scientific presentations)