Principal Engineer, Cloud Ops

Iambic Iambic · Pharma · Boston, MA · Technology

This role is for a Principal Engineer, Cloud Ops at Iambic Therapeutics, a company developing an AI-driven drug discovery platform. The engineer will support and drive the Cloud Ops roadmap, focusing on designing, building, and operating scalable AWS cloud infrastructure, networking, and automation (IaC). They will also ensure reliability, performance, cost efficiency, and security (ISO 27001 compliance), and improve observability and CI/CD pipelines. While working closely with the ML organization, the core focus is on the operational infrastructure supporting these efforts, including understanding ML deployment challenges.

What you'd actually do

  1. Support and contribute to the Cloud Ops roadmap, aligning infrastructure initiatives with business priorities.
  2. Provide technical leadership and drive architecture decisions across platform and infrastructure teams.
  3. Lead the design and evolution of scalable, highly available AWS cloud infrastructure.
  4. Build and operate production systems with a strong focus on reliability, performance, and cost efficiency.
  5. Design and manage cloud networking (VPN, VPC, routing, DNS, load balancing, secure connectivity).

Skills

Required

  • Minimum of 12 years of related experience with a bachelor’s degree; or 10 years and a master’s degree; or equivalent experience.
  • Strong understanding of CI/CD pipelines.
  • Strong Infrastructure as Code skills – for example in Docker, Packer/Ansible and Terraform/Terragrunt.
  • Strong understanding of AWS services and underlying technologies such as AWS IAM service and managing Kubernetes as a service (AWS EKS) including managing zero-downtime upgrades and debugging issues with deployments, controllers, etc. Deployed in the cluster.
  • Strong understanding of computer networks: TCP/IP protocols, IP block allocation across an organization, Routing and VPN protocols, AWS networking: VPCs, Transit Gateways, Customer Gateways, VPNs, flow logs, security groups, NACLs, etc., Cloudflare networking experience.
  • Understanding of issues facing ML deployments including model training and inference challenges.
  • Ability to communicate with a variety of teams including IT, Computational Scientists, Software Developers, Cloud Ops and ML engineers

What the JD emphasized

  • ISO 27001 compliant Cloud Ops processes
  • ISO 27001 compliance frameworks