Principal Scientist, Data Science - Ddsai - Therapeutics Development Supply

Johnson & Johnson Johnson & Johnson · Pharma · Spring House, PA +2

Seeking a Principal Data Scientist to design, build, validate, and deliver applied AI/ML and statistical modeling solutions for Drug Product Development & Supply (DPDS), focusing on Therapeutics Development & Supply (TDS). The role involves partnering with various teams to create practical, high-impact models supporting CMC development, pharmaceutical product development, dossier preparation, technical development, and clinical supply. Responsibilities include hands-on model development, feature engineering, diagnostics, error analysis, uncertainty assessment, developing reusable workflows using Python and cloud services, applying software engineering best practices, and providing technical guidance.

What you'd actually do

  1. Serve as a senior hands-on individual contributor responsible for personally designing, coding, testing, validating, and refining applied AI/ML models for high-value TDS use cases.
  2. Translate complex scientific and business questions into tractable modeling problems, selecting fit-for-purpose methods based on the data, decision context, assumptions, and expected business impact.
  3. Conduct rigorous exploratory analysis, feature engineering, diagnostics, error analysis, sensitivity analysis, and uncertainty assessment to ensure models are credible, robust, and actionable.
  4. Develop robust, reusable analytical workflows and modeling assets using Python and modern data science tooling, including cloud-based services.
  5. Apply software engineering best practices, including version control, modular code design, testing, documentation, reproducibility, and code review.

Skills

Required

  • Python programming
  • applied data science
  • machine learning
  • statistical modeling
  • AI/ML solution development
  • scientific computing
  • version control
  • testing
  • documentation
  • reproducibility
  • code review
  • stakeholder engagement
  • communication skills

Nice to have

  • Ph.D. in Mathematics, Statistics, Engineering, Chemical Engineering, Computer Science, Data Science, Ope

What the JD emphasized

  • hands-on technical individual contributor
  • designing, building, validating, and delivering applied AI/ML and statistical modeling solutions
  • hands-on applied AI/ML model development
  • personally designing, coding, testing, validating, and refining applied AI/ML models
  • rigorous exploratory analysis, feature engineering, diagnostics, error analysis, sensitivity analysis, and uncertainty assessment
  • develop robust, reusable analytical workflows and modeling assets
  • apply software engineering best practices
  • strong quantitative depth
  • proven record of delivering analytical solutions with real-world impact
  • strong Python programming skills
  • strong applied problem-solving skills
  • strong stakeholder engagement and communication skills

Other signals

  • applied AI/ML model development
  • designing, building, validating, and delivering applied AI/ML and statistical modeling solutions
  • translate complex scientific and business questions into tractable modeling problems
  • conduct rigorous exploratory analysis, feature engineering, diagnostics, error analysis, sensitivity analysis, and uncertainty assessment
  • develop robust, reusable analytical workflows and modeling assets using Python and modern data science tooling
  • apply software engineering best practices
  • provide technical guidance to junior team members