Principal Solution Architect - Therapeutics Development

Johnson & Johnson Johnson & Johnson · Pharma · Beerse, Antwerp, Belgium +2

The Principal Solution Architect for Therapeutics Development at Johnson & Johnson will define and maintain the technology architecture vision, roadmap, and standards for next-generation R&D capabilities. This role involves providing architectural leadership, driving the evaluation and selection of technical solutions, and ensuring compliance with security, privacy, and regulatory standards. The architect will also monitor emerging technology trends, including AI/ML, and conduct feasibility assessments for new capabilities, collaborating with product teams to leverage enterprise capabilities and ensure the successful implementation of architectural designs.

What you'd actually do

  1. Define and maintain the Technology architecture vision, roadmap, and standards for the Therapeutics Development domain. Align technology landscape across squads to promote interoperability, modularity, and scalability.
  2. Provide architectural leadership across squads, ensuring alignment to enterprise patterns, reusable components, and modern engineering practices. And ensure compliance with security, privacy, data governance, and regulatory standards.
  3. Drive evaluation, design, and selection of technical solution options; build, test, and validate architectural concepts and prototypes. Translate complex business and scientific requirements into scalable and actionable technical designs.
  4. Monitor emerging technology trends in lab automation, cloud engineering, AI/ML, and scientific computing. Conduct research spikes and feasibility assessments for new capabilities relevant to Therapeutics Development workflows and workflow automation
  5. Collaborate with product owner on the actual implementation, meaning building out the correct team, resourcing, budget and continued engagement to ensure the architecture is implemented as intended.

Skills

Required

  • Bachelor’s degree or equivalent experience in a relevant scientific or technical subject area
  • At least 3 years of experience enabling or developing scientific IT capabilities, in (bio)pharmaceutical discovery or early development.
  • Strong foundational skills in IT, including database design, data engineering, cloud computing, and architecture principles.
  • Proven track record to translate complex scientific and business needs into practical technical solutions.
  • Proficiency in Python or a similar programming language for prototyping, integration, or workflow automation.
  • Demonstrated experience owning products or platforms throughout their lifecycle in a multi disciplinary team environment.
  • Strong interpersonal and negotiation skills with the ability to influence and build trusted partnerships across functions.
  • Experience in leading a team of external resources
  • Experience delivering high‑quality digital solutions including dependency management, release planning, change control, validation, and governance.

Nice to have

  • Master’s preferred.
  • Experience with lab‑specific systems such as ELN, LIMS,SDMS, or automation control software.
  • Understanding of GxP or regulated system requirements.
  • Familiarity with SDLC methodologies and software validation practices.
  • Change Management
  • Compliance Management
  • Consulting
  • Developing Others
  • Emerging Technologies
  • Enterprise IT Governance
  • Inclusive Leadership
  • Information Security Management System (ISMS)
  • Information Technology Strategies
  • IT Architecture
  • Leadership
  • Product Configuration
  • Requirements Analysis
  • Resource Allocation
  • Solution Architecture
  • Team Management
  • Technical Credibility

What the JD emphasized

  • Ensure compliance with security, privacy, data governance, and regulatory standards.
  • Experience delivering high‑quality digital solutions including dependency management, release planning, change control, validation, and governance.
  • Understanding of GxP or regulated system requirements.