Senior / Principal Technical Program Manager, Life Sciences AI

Lila Sciences Lila Sciences · AI Frontier · Alewife, Cambridge, MA +2 · AI

This role is for a Senior/Principal Technical Program Manager to bring structure, accountability, and delivery cadence to the Life Sciences AI organization. The role involves coordinating between model researchers, computational and wet-lab scientists, automation and software teams, and the broader organization to drive program planning, status, milestone tracking, and risk management for AI-driven scientific discovery.

What you'd actually do

  1. Establish and operate the delivery cadence and rhythm for the Life Sciences AI organization — driving program planning, status, milestone tracking, and risk management across foundation model research, evaluation, and integration with Lila's closed-loop discovery engine.
  2. Serve as the key communication interface between LSAI and partner organizations (model training, experimental science, automation, software, product, and leadership); set up the organizational information flows that allow this communication to happen with speed at scale.
  3. Drive accountability across distributed, cross-functional teams without relying on direct authority; build consensus through clear communication and sound judgment.
  4. Translate research priorities into structured, accountable program execution: define workstreams, milestones, dependencies, and risks across biological sequence design, structure prediction, multimodal scientific reasoning, and other LSAI program areas.
  5. Partner with experimental scientists and computational biologists to keep the Lab-in-the-Loop feedback cycle on schedule — ensuring data generation, model training, and experimental validation stay synchronized.

Skills

Required

  • Program or project management experience
  • Technology, AI/ML, or life sciences environments experience
  • Leading cross-functional programs
  • Analytical and problem-solving skills
  • Translating technical and scientific requirements into roadmaps
  • Driving accountability without direct authority
  • Exceptional written and verbal communication skills
  • Producing executive-quality documents, roadmaps, and updates

Nice to have

  • Direct experience in AI/ML research or product organizations
  • Program management or research operations capacity
  • Working familiarity with foundation models, generative AI, or ML for biology
  • Engaging credibly with researchers
  • Exposure to experimental science workflows
  • Exposure to closed-loop discovery systems
  • Managing programs spanning research, evaluation, and integration
  • Driving rapid experimentation and program iteration

What the JD emphasized

  • 8+ years of program or project management experience in technology, AI/ML, or life sciences environments.
  • Proven experience leading cross-functional programs and driving them to successful completion under tight delivery timelines.
  • Track record of driving accountability without direct authority across engineering, research, and scientific stakeholders.
  • Exceptional written and verbal communication skills; track record of producing executive-quality documents, roadmaps, and updates that drive decisions.