Senior Research Associate / Associate Scientist, Targeted Lnp Delivery

Lila Sciences Lila Sciences · AI Frontier · One Charles Park, Cambridge, MA · Autonomous Science Platform

Seeking a Senior Research Associate/Associate Scientist to focus on formulating, functionalizing, and characterizing targeted lipid nanoparticles (LNPs) for drug delivery. The role involves hands-on expertise in LNP formulation, bioconjugation, protein characterization, and automation to enable a high-throughput closed-loop screening cascade. Collaboration with chemistry, machine learning, and data science teams is key to developing next-generation tools for targeted nucleic acid delivery.

What you'd actually do

  1. Design, execute, and characterize (DLS, ribogreen, TNS, etc.) LNP formulations across multiple scales and mixing modalities
  2. Develop and refine high-throughput ligand conjugation and purification methods, employing automation and robotics to increase throughput
  3. Collaborate with cell assay and antibody specialists to screen hits across a variety of tissue targets in _in vivo_ models
  4. Collaborate with chemists, biologists, engineers, and data scientists to document systems, share insights, and refine best practices in autonomous flow chemistry
  5. Write, implement, and maintain Standard Operating Procedures (SOPs) for both existing and new lab processes

Skills

Required

  • MSc in Chemical Engineering, Biomedical Engineering, Pharmaceutical Sciences, or a related field with 3+ years, or BSc with 5+ years, of hands-on experience in targeted LNP production, or related experience
  • Strong working knowledge of bioanalytical techniques (e.g., DLS, fluorescence spectroscopy, electrophoresis, in vitro assays)
  • Experience with protein and antibody design and characterization
  • Familiarity with automation and high-throughput workflows

Nice to have

  • Industry experience strongly preferred

What the JD emphasized

  • hands-on expertise in LNP formulation and characterization
  • automation technologies
  • high-throughput closed-loop screening cascade
  • high-throughput next-generation tools
  • automation and high-throughput workflows

Other signals

  • closed-loop screening cascade
  • high-throughput next-generation tools
  • automation and robotics
  • chemistry machine learning
  • data science teams