Senior Scientist

Merck Merck · Pharma · NJ

The Senior Scientist, Process Cell Sciences (PCS) role at Merck focuses on developing and characterizing mammalian production cell lines for biologics pipeline. This involves expertise in molecular biology, cell biology, synthetic biology, and integrating systems biology models with large-scale datasets. The role requires experience in cell line development workflow, genetic characterization techniques, and potentially regulatory filing.

What you'd actually do

  1. develop and characterize mammalian production cell lines to support innovative biologics pipeline
  2. executing complex study designs requiring highly organized data collection and management
  3. proactive planning, trouble shooting and successful execution of complex experimental protocols for cell line development and technology assessment
  4. serve as a technical lead and functional area representative on project teams

Skills

Required

  • Biological Sciences
  • Data Analysis
  • Genome Editing
  • Library Construction
  • Mammalian Cell Culture
  • Molecular Biology
  • Synthetic Biology
  • Technical Writing
  • Vector Design

Nice to have

  • Cell Biology
  • Cell Line Development
  • regulatory filing
  • preparing relevant documentation
  • regulatory guidelines related to biologics cell line development and cell bank characterization
  • genomics
  • transcriptomics
  • proteomics
  • genome editing technologies
  • database and statistical software (e.g., JMP, Spotfire)
  • library construction and data management for DNA-seq and RNA-seq workflows

What the JD emphasized

  • cell line development experience in industry
  • hands-on experience of molecular subcloning, vector design, and mammalian cell culture
  • industrial cell line development workflow
  • integrating systems biology models with large-scale datasets
  • cell line genetic characterization techniques