Senior Scientist – Combination Products Characterization

Johnson & Johnson Johnson & Johnson · Pharma · Beerse, Antwerp, Belgium

The Senior Scientist will join the Advanced Materials Characterization and Investigations (AMCI) group within Analytical Development. This lab-based role will provide hands-on characterization of drug–device combination products and polymer-based components, generating actionable, engineering-focused insights. Responsibilities include planning, executing, and optimizing mechanical property testing, conducting dimensional metrology and fit/form assessments, and applying IR spectroscopy and imaging/microscopy to determine polymer identity, morphology, and structure–property relationships. The role aims to produce high-quality mechanical, dimensional, spectroscopic and imaging datasets, interpret and communicate results, and translate findings into clear recommendations for product development and lifecycle management, while maintaining awareness of regulatory requirements.

What you'd actually do

  1. Perform advanced materials characterization experiments using mechanical testers (e.g. Zwick, Instron), imaging and spectroscopy instruments (e.g. IR, SEM, Optical Microscopy, XCT, etc.), ensuring high-quality sample preparation and optimal instrument operation.
  2. Collaborate closely at the interface between Active Pharmaceutical Ingredients (API), Drug Products (DP), Device (DDS) teams to enhance product development, i.e. selecting optimal API quality with respect to physical material attributes and DP formulation & manufacturing platforms
  3. Continuously evaluate analytical characterization strategies to provide the best support possible to the project teams in CMC development
  4. Drive internal & external innovation projects with respect to characterization approaches and workflows. This includes the assessment of novel characterization techniques and modeling.
  5. Analyze and interpret results, providing clear, data-driven insights to address product quality, structure, and performance questions.

Skills

Required

  • PhD degree (or equivalent) in Polymer and material Sciences (preferred), Biomedical Engineering, Pharmaceutical Sciences, Physics, or a related field.
  • Prior practical laboratory experience and/or knowledge in mechanical properties testing (e.g. uniaxial testing, injectability, 3-point bending, detachment force)
  • Knowledge of statistical methodologies incl. PCA/PLS.
  • Strong analytical and problem-solving abilities with attention to detail in experimental work.

Nice to have

  • Prior work with drug-device combination products and medical devices is a plus
  • Prior knowledge/experience in at least one of the following advanced imaging techniques is a plus: IR/Raman Microscopy, SEM, Optical Microscopy, XCT and/or THz imaging.

What the JD emphasized

  • drug–device combination products
  • polymer-based components
  • mechanical property testing
  • dimensional metrology
  • IR spectroscopy and imaging/microscopy
  • polymer identity, morphology, and structure–property relationships
  • design verification/validation
  • troubleshooting
  • lifecycle product development
  • regulatory and packaging requirements
  • devices and combination products
  • test strategies, documentation, and reporting
  • engineering requirements into characterization strategies
  • test parameters and acceptance criteria
  • develop and validate methods
  • product and process evaluations
  • combination product lifecycle
  • Active Pharmaceutical Ingredients (API)
  • Drug Products (DP)
  • Device (DDS) teams
  • CMC development
  • novel characterization techniques and modeling
  • product quality, structure, and performance questions
  • GMP and safety