Senior Scientist (m/f/d), Preclinical Development in Animal Health

Merck Merck · Pharma · Rheinland-Pfalz, Germany

Senior Scientist role in Preclinical Development for Animal Health at Merck, focusing on supporting R&D, assessing compound profiles, planning and conducting studies (toxicology, safety, pharmacokinetics, metabolism), preparing regulatory submissions, and collaborating with external experts and project teams. Requires a Veterinary Medicine degree with PhD, experience in R&D within the veterinary pharmaceutical environment, and expertise in pharmacology, metabolism, and toxicology.

What you'd actually do

  1. Scientifically support Research and Development activities for new and established products in animal health
  2. Compile and assess pharmacological and toxicological profiles of chemical compounds by literature search and testing
  3. Plan, conduct, and evaluate in-house or outsourced in-vitro and in-vivo studies according to GLP guidelines, including toxicology, target animal safety, pharmacokinetics, metabolism, and residue depletion.
  4. Prepare expert reports, regulatory submissions and scientific presentations in English for authorities and internal stakeholders.
  5. Maintain and extend engagement with contract research organizations, external experts, and universities.

Skills

Required

  • ADME
  • Biochemical Assays
  • Biosecurity
  • Cell-Based Assays
  • Chemical Synthesis
  • Detail-Oriented
  • Drug Metabolism
  • Environmental Toxicology
  • Flow Cytometry
  • High Resolution Mass Spectrometry (HRMS)
  • IACUC Protocols
  • Ligand Binding Assay
  • Liquid Chromatography-Mass Spectrometry (LC-MS)
  • Literature Searches
  • Mass Spectrometry Analysis
  • Metabolite Identification
  • Partnership Strategy
  • Pharmacodynamics
  • Pharmacokinetics
  • Pharmacotherapeutics
  • Scientific Research
  • Teamwork
  • Toxicity Studies
  • Toxicology
  • Veterinary Medicine

What the JD emphasized

  • GLP guidelines