Job Description
We are seeking a Scientist II who is passionate about developing complex in vitro microphysiological organ-on-chip systems (MPS) and bioprinted models for drug discovery and development. In this role, the scientist will perform hands-on experimentation and provide support to advance the team’s biofabrication efforts.
This position is based on-site in Cambridge, MA, supporting day-to-day laboratory workflows and assisting with model development within a collaborative research environment.
Key Responsibilities
- Support the biofabrication and maintenance of microphysiological systems and bioprinted models.
- Perform routine mammalian cell culture while maintaining a high level of aseptic technique.
- Prepare and handle hydrogels/ECM for use in 3D culture (MPS and bioprinted) platforms.
- Assist in immunofluorescence staining, imaging, and analysis workflows.
- Reconstitute, aliquot, and prepare reagents and media.
- Execute multi-step experimental protocols and workflows.
- Document experimental procedures, observations, and results in electronic lab notebook.
- Assist with inventory management, ordering, and general lab maintenance.
- Support both general and project-specific laboratory operations as project needs evolve.
- Collaborate across different functional teams/locations.
**Required Education: High School Diploma or GED required. Bachelor’s Degree or Master’s Degree preferred. **(B.S./B.A. in Bioengineering, Biology, Biomedical Engineering, Cell & Molecular Biology, Immunology, or a related field with minimum of 1 year of relevant experience or Master’s Degree)
Required Experience and Skills
- Minimum of 2 years of experience in mammalian cell culture and aseptic technique.
- Experience preparing and handling biomaterials or hydrogels for 3D culture applications.
- Experience working with MPS models, bioprinted platforms, or other 3D cell culture technologies.
- Familiarity with basic microscopy techniques for assessing cell health and experimental progress.
- Strong attention to detail, organizational skills, and accurate documentation practices.
- Demonstrated ability to execute experimental protocols and work with collaborators.
- Ability to work on-site, follow established protocols, and meet deadlines.
- Enthusiastic, self-motivated, and eager to learn new workflows.
Preferred Experience and Skills
- Experience with stem cell culture or differentiation workflows.
- Experience with stem cell-derived organoid models.
- Experience working with MIMETAS organ-on-chip, or similar high throughput, platform.
- Experience working in pharmaceutical drug discovery or development.
- Data analysis experience using Matlab, R, and/or Python.
- Experience with nucleofection.
#eligibleforerp
MSJR
**Required Skills: **
3D Cell Culture, 3D Cultures, Aseptic Technique, Bioprinting, Bioproduction, Mammalian Cell Culture
**Preferred Skills: **
Current Employees apply HERE
Current Contingent Workers apply HERE
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As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
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U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.
The salary range for this role is
$87,300.00 - $137,400.00
This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
**Search Firm Representatives Please Read Carefully ** Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
**Employee Status: **
Regular
Relocation:
No relocation
VISA Sponsorship:
No
Travel Requirements:
10%
Flexible Work Arrangements:
Not Applicable
Shift:
Not Indicated
Valid Driving License:
No
Hazardous Material(s):
N/A
Job Posting End Date:
05/16/2026
***A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. **