The JP Economics and Decision Sciences team is a central science team that applies rigorous economic theory, causal inference methods, and machine learning to solve complex business challenges across the JP marketplace and beyond. We work closely with JP business leaders to drive change at Amazon, focusing on solving long-term, ambiguous problems while providing advisory support for short-term business pain points. Key topics include pricing, product selection, delivery speed, profitability, and customer experience. We tackle these issues by building novel economic and econometric models, machine learning systems, and high-impact experiments which we integrate into business, financial, and system-level decision making. Our work is highly collaborative and we regularly partner with JP-, EU-, and US-based interdisciplinary teams.