Seeking a Scientist, MCICC to drive innovation in AI-powered drug evaluation and development. This role focuses on building and optimizing advanced AI systems, including large language models (LLMs) and molecular generation and property prediction models. The ideal candidate will combine deep technical expertise with domain knowledge in pharmaceutical R&D, enabling rapid iteration and deployment of cutting-edge solutions.

AI Research Scientist with 1-2+ years of experience in healthcare IT, focusing on research, assessments, and technical evaluations of AI models and frameworks to solve internal problems and enhance generative AI capabilities. The role involves creating proof-of-concepts, staying updated on AI research, and mentoring colleagues. Requires a strong understanding of AI research landscape, hands-on Python development, and familiarity with GenAI, deep learning, NLP, CV, and ML frameworks, preferably within a cloud environment.

Merck is seeking a computational biologist with expertise in image analysis to join their Translational Genome Analytics research team. The role involves applying AI/ML-based analytics to large multi-omics imaging and functional genomics datasets for target and biomarker discovery in drug development, with a focus on Oncology. The candidate will collaborate with cross-functional teams and contribute to quantitative analysis of imaging datasets and integration of machine learning with phenotypic screens.

Distinguished Scientist role in Vaccines & Advanced Biotechnologies Process R&D at Merck, focusing on the process development and clinical manufacturing of vaccine drug substances. The role involves crafting scientific strategy, fostering collaborations, mentoring talent, and advising on complex technical challenges, with a requirement for experience in CMC leadership and regulatory submissions. While AI/ML is mentioned as an area of understanding, it is not the core craft of the role.

This role focuses on creating next-generation mammalian cell lines for therapeutic development by designing synthetic genetic circuits, managing multi-omics datasets, and utilizing NGS. It involves applying machine learning (ML) or deep learning (DL) models to inform experimental design and predict cell line performance, alongside computational modeling of cellular pathways and metabolism. The role requires strong programming skills in Python or R for biological data analysis and experience with Linux/Unix environments.

This role focuses on curating, preprocessing, and integrating large-scale proteomics, genetics, and multi-omics datasets for biomarker and target discovery. It involves exploring and developing statistical and AI/ML approaches for these purposes, and building causal networks. The role is within a Research and Development division at Merck, specifically in the Precision Genetics group.

This postdoctoral research fellow role focuses on developing innovative high-throughput crystallization strategies and methodologies using automation and machine learning to discover new solid forms in pharmaceutical research. The role involves characterizing these forms using various analytical techniques and building analytical methods to process large datasets.

This role is responsible for planning and executing clinical-trial biomarkers, focusing on compliant and efficient biospecimen collection, assay execution, and data delivery within the Immunology and Oncology therapeutic areas. The Senior Scientist will partner with scientific and operational colleagues to ensure high-quality biomarker data for clinical trials and translational research.

Principal Scientist role in Oncology In Vivo Pharmacology at Merck, focusing on directing reverse-translational activities, leading drug discovery projects, building alliances, championing new technologies like spatial biology, and collaborating with cross-functional teams and external partners. Responsibilities include performing preclinical experiments, managing external studies, leading a team of scientists, and representing the department in governance forums. Requires a PhD or MS/BS with extensive experience in Oncology drug discovery and in vivo pharmacology, with specific skills in preclinical models, spatial biology, and team management.

Seeking a Senior Scientist in Stromal Immunology to work in a lab-based role, evaluating and applying novel experimental approaches to identify and validate therapeutic targets for inflammatory and autoimmune diseases. The role involves designing and executing experiments, analyzing complex datasets, and contributing to the development of new therapies.

Internship opportunity within Merck's Discovery & Technology department focused on improving a cell line for viral antigen production. The role involves combining molecular techniques with pilot scale cell culturing to create an in vitro cell substrate for high antigen yields in large-scale manufacturing. The intern will execute experiments, troubleshoot, and document findings, contributing to vaccine development.

Distinguished Scientist (Executive Director) at Merck, leading clinical research for oncology indications and vaccines. Responsibilities include planning, directing, and overseeing the entire clinical development cycle, from study design to regulatory reporting and publication. The role involves managing cross-functional teams, interacting with key opinion leaders, and maintaining scientific knowledge in the field.

Junior Veterinary Researcher role focused on conducting research studies for veterinary drug development, including study planning, execution, and reporting, while adhering to GLP/GCP guidelines. Responsibilities also include sample processing, financial administration, and lab equipment maintenance.

Principal Scientist role focused on downstream process development for biotherapeutics at Merck. The role involves designing purification processes, developing technical strategies, and innovating manufacturing technologies. It requires collaboration with cross-functional teams, publishing research, and mentoring staff. While AI/ML is mentioned as a preferred skill, it is not the core craft of the role.

Merck is seeking a Regional R&D Director for their Ruminants division. This leadership role involves managing, coaching, and developing a team of 13 scientists in Boxmeer, NL. The director will be responsible for biological research and development, leading to the timely launch of commercially viable Ruminants Biologicals. The role requires a PhD in life sciences with significant experience in vaccine development for animal health, proven team management skills, and a results-driven, innovative mindset. Collaboration with global teams in Marketing, Commercial, Manufacturing, Regulatory Affairs, and Legal is essential.

Principal Scientist, Drug Discovery role at Merck, focusing on identifying new molecular entities and technologies for animal health. The role involves leading research programs from ideation through early research and proof-of-concept to development, interfacing with internal and external stakeholders. Requires a DVM/VMD and PhD in experimental pharmacology with at least 8 years of industry experience in drug discovery or preclinical research, with expertise in specific therapeutic areas and knowledge of regulatory aspects.

Senior Scientist in Biologics Analytical R&D at Merck, focused on developing, qualifying, and troubleshooting analytical methods for therapeutic proteins. Requires a strong background in separations science (UPLC/HPLC, CE) and experience with assay development for release, characterization, and stability testing. The role involves scientific leadership, collaboration, and authoring technical reports and regulatory filings.

This role focuses on generating real-world data and evidence to inform clinical program design, access strategies, and policy for high-priority therapeutic areas, with a specific emphasis on health equity. The Associate Director will lead mixed-methods studies, integrate social determinants of health and patient-reported measures, develop external partnerships, and translate findings into actionable recommendations for clinical protocols, site selection, and policy. The role requires expertise in quantitative and qualitative research methods, data analysis, and collaboration with diverse stakeholders, ensuring research adheres to ethical and regulatory standards.

Senior Scientist role focused on leading animal vaccine development projects from discovery through licensure, involving experimental design, data analysis, cross-functional team leadership, and regulatory compliance within a regulated environment.

Associate Principal Scientist role focused on designing, coordinating, monitoring, and reporting clinical laboratory and field studies for companion animal and livestock products, ensuring compliance with GCP and GLP guidelines. The role involves study team leadership, investigator selection, permit applications, and final report preparation, with a strong emphasis on scientific and regulatory requirements within the animal health sector.

This role is for a Sr. Director of Epidemiology in Hematology at Merck, focusing on leading a team of epidemiologists to conduct and oversee epidemiologic research for assigned company assets and indications. Responsibilities include scientific oversight, planning, design, and execution of studies related to clinical development, safety, effectiveness, and observational research. The role involves presenting research plans, interacting with regulatory agencies, and managing a team. It requires extensive experience in epidemiologic projects and a strong track record in research publications.

Scientist with a background in Oncology to join a cross-functional team within Discovery Oncology. Primary responsibilities will include designing and executing experiments in the laboratory to validate novel targets for our early discovery pipeline and to support drug discovery efforts.

Scientist role at Merck focused on molecular discovery, specifically optimizing next-generation sequencing for in vitro display campaigns to discover and engineer therapeutic candidates. Requires strong molecular biology and NGS understanding, with collaboration across biology, protein engineering, and data science teams.

Associate Principal Scientist role in R&D Clinical Research for General and Specialty Medicine at Merck, focusing on oncology-adjacent areas like General Medicine, Infectious Diseases, and Vaccines. Responsibilities include providing medical expertise to development teams, reviewing documents, leading clinical development plans in Japan in collaboration with US headquarters, engaging with scientific leaders, and supporting academic presentations/publications. Requires an MD with 5+ years of clinical experience in cardiology or equivalent, strong collaboration, English negotiation/speaking/writing skills, and fluent Japanese.

This role focuses on developing sterile drug products for biologics, involving formulation, composition, packaging, and process selection. It leverages smart experimental design, analytical tools, and predictive approaches to inform molecule and process selection, aiming to translate preclinical candidates into non-oral drug products. The role requires a Master's or Ph.D. in a related scientific field and experience in areas like protein stability, formulation screening, and process development.

Senior Scientist in Biologics Analytical R&D at Merck, focused on developing, qualifying, and implementing analytical methods for biologics drug substances and products. Requires expertise in separations science, UPLC/HPLC, CE, and data analysis for characterization, release, and stability testing. Role involves scientific leadership, collaboration, and contributing to regulatory filings and publications.

Associate Scientist role focused on formulation development and manufacturing of sterile pharmaceutical products, from preclinical studies to commercialization. Requires a BS degree in a relevant scientific field and strong collaboration skills. The role involves executing laboratory experiments, data interpretation, and supporting manufacturing operations in GXP environments.

Senior Scientist in Merck's Biologics Analytical Research & Development department focused on solving complex analytical problems at the interface of biology, chemistry, and lab informatics for drug development. Responsibilities include method development, qualification, implementation, troubleshooting, and transfer for monoclonal proteins and other complex therapeutic proteins. Requires strong background in separations science (UPLC/HPLC, CE), assay development, and understanding of Critical Quality Attributes/QbD/DOE principles. Experience with regulatory filings and publications is expected.

Senior Scientist in Biologics Analytical Research & Development at Merck, focused on solving complex analytical problems for drug substance and product development. Responsibilities include method development, qualification, implementation, troubleshooting, and transfer for monoclonal proteins and other complex therapeutic proteins. Requires strong background in separations science (UPLC/HPLC, CE), assay development, and understanding of Critical Quality Attributes. Role involves authoring technical reports and regulatory filings, with a strong emphasis on scientific leadership and collaboration.

This role is for a Regional Medical Scientific Director focused on vaccines, engaging with scientific leaders to exchange medical and scientific information, support clinical trials, and gather feedback. It requires an advanced degree (MD, DO, PharmD, PhD, DNP) and experience in vaccines and vaccine-preventable diseases, with a strong understanding of regulatory guidelines like HIPAA.

Seeking a Scientific Director for Translational PK/PD, focusing on mechanistic modeling for drug discovery of biologics, protein therapeutics, and peptides. The role involves leading development and supervision of PBPK and QSP modeling strategies, integrating in vitro and in vivo data, and guiding software developers for automated workflows. Requires expert mathematical modeling skills and experience with standard modeling software.

Seeking a Scientist II to develop and support biofabrication efforts for in vitro microphysiological organ-on-chip systems (MPS) and bioprinted models for drug discovery and development. Responsibilities include hands-on experimentation, cell culture, hydrogel preparation, imaging, and data documentation within a collaborative research environment.

The Senior Scientist, Biopharmaceutics role at Merck focuses on developing and registering new drug products, specifically non-oral dosage forms. The role involves representing the biopharmaceutics team in drug product development, driving biopharmaceutics strategy, and developing next-generation physiologically-based modeling and simulation tools. Key responsibilities include identifying biopharmaceutics risks, influencing formulation strategies, developing quantitative absorption models, and contributing to internal and external innovation in biopharmaceutics and quantitative modeling.

Senior Scientist role in Preclinical Development for Animal Health at Merck, focusing on supporting R&D, assessing compound profiles, planning and conducting studies (toxicology, safety, pharmacokinetics, metabolism), preparing regulatory submissions, and collaborating with external experts and project teams. Requires a Veterinary Medicine degree with PhD, experience in R&D within the veterinary pharmaceutical environment, and expertise in pharmacology, metabolism, and toxicology.

Senior Scientist role in Preclinical Development for Animal Health at Merck, focusing on supporting R&D, assessing compound profiles, planning and conducting studies (toxicology, safety, pharmacokinetics, metabolism), preparing regulatory submissions, and collaborating with external experts and project teams. Requires a Veterinary Medicine degree with PhD, experience in R&D within the veterinary pharmaceutical environment, and expertise in pharmacology, metabolism, and toxicology.

Senior Scientist role in Preclinical Development focusing on Immunology for Animal Health at Merck. Responsibilities include scientific support for R&D, compiling and assessing profiles of compounds, planning and evaluating studies (toxicology, safety, pharmacokinetics, immunogenicity), designing and overseeing immunology and monoclonal antibody studies, and compiling reports for regulatory submissions. Requires a Veterinary Medicine degree with a PhD, experience in R&D (preferably veterinary pharma), managing animal studies (GLP), and profound knowledge in pharmacology, toxicology, and immunology. Hands-on experience with immunological assays is essential. Fluency in English and German is required.

Senior Principal Scientist role at Merck focused on planning and directing clinical research activities for new or marketed Oncology medicines. Responsibilities include study design, monitoring, analysis, regulatory reporting, and publication, managing the entire cycle of clinical development. Requires MD or MD/PhD with experience in industry or academia and a strong background in biomedical research.

The Medical & Scientific Liaison (MSL) role in Oncology at Merck focuses on engaging with Healthcare Professionals and Researchers to provide scientific and therapeutic information. The role involves in-depth scientific exchange, knowledge transfer initiatives, and supporting the development and execution of the Oncology Medical Affairs Plan. Key responsibilities include managing budgets, providing medical/scientific advice to internal teams, and supporting regulatory reporting. The position requires a PhD or equivalent, at least 2 years of MSL experience, and strong knowledge of oncology and pharmaceutical industry standards.

This role is for a Regional Medical Scientific Director at Merck, focusing on the COPD program. The position involves engaging with Scientific Leaders to exchange scientific and medical information, supporting clinical trials, and gathering scientific insights. The role requires a PhD or equivalent, significant therapeutic area experience, and a strong understanding of regulatory guidelines like HIPAA.

Seeking a scientist with expertise in mass spectrometry-based protein, protein conjugation, or oligonucleotide/polysaccharide characterization, with strong proteomics and data science skills, to support vaccine programs. Responsibilities include conducting experiments, developing new methods, processing data, and documenting findings.

Scientist in Biologics Process Research & Development (BPR&D) at Merck, focusing on developing innovative and robust manufacturing processes for biotherapeutics. This role involves experimental design, process development, and collaboration across various scientific and manufacturing functions, with a potential to integrate digital tools for process design.

Principal Scientist in Biologics Analytical R&D at Merck, focused on defining analytical strategy and leading a team to solve complex analytical problems in biologics API development. Requires extensive experience in biologics analysis, assay development, and regulatory filings.

Associate Scientist in Biologics Process Research & Development (BPR&D) at Merck, focusing on designing, developing, and executing robust processes for biological products. The role involves contributing to innovative manufacturing technologies, conducting experiments for unit operations, and collaborating across R&D and manufacturing teams. Experience with bioprocessing, cell culture, protein purification, and data analysis is required.

This role at Merck focuses on Biologics Process Research & Development (BPR&D), aiming to efficiently develop innovative and robust manufacturing processes for biotherapeutics. Responsibilities include developing disruptive technologies, applying scientific principles to solve process development challenges, designing and conducting lab/pilot-scale studies, and collaborating with cross-functional teams. The role requires a Bachelor's, Master's, or PhD in a relevant scientific or engineering field with several years of experience, and proficiency in experimental design, data analysis, and problem-solving. Experience in upstream or downstream bioprocessing is essential. While AI/ML is mentioned as a preferred skill, the core of the role is in bioprocess development, not AI/ML model building.

The Principal Scientist in Outcomes Research will plan and manage real-world evidence and non-interventional research for lung cancer products. This role involves designing studies, developing protocols, analyzing data, and creating dossiers for payers and HTA agencies, aiming to ensure patient access and improve health outcomes.

Medical Advisor for Cardiology at Merck, responsible for developing and executing Medical Affairs strategic plans, engaging with the medical/scientific community, and providing asset issue resolution support. Requires MD, PhD, or PharmD with clinical/research experience and strong communication skills.

Medical Advisor for Oncology role at Merck, focusing on developing and executing Medical Affairs strategic plans, engaging with the medical/scientific community, and providing support for asset issue resolution. Requires an MD, PhD, or PharmD with clinical/research experience and strong knowledge of pharmaceutical industry guidelines and regulatory frameworks.

Seeking a Sr. Scientist in Analytical Research & Development focused on the physicochemical characterization of pharmaceutical materials. The role involves tackling scientific challenges related to crystallization, polymorph selection, drug-excipient compatibility, and physical stability of APIs and drug products. Requires expertise in materials science or physical chemistry with characterization techniques like X-ray diffraction and thermal analysis. Collaboration with cross-functional teams and external communities is expected.